Made by Ms. Sindhu Vas, M.Sc. Food Science & Nutrition Medically Reviewed by: Dr. Prajna, BAMS, MD Ayurveda…
Read MoreKnown as ‘madhumeha’ in Ayurveda, diabetes is a growing cause of concern worldwide. This condition is indicated by high levels of blood sugar or glucose. A hormone known as insulin, which is produced by your pancreas, is responsible for moving sugar from your blood into cells where it’s used for energy. But in people with diabetes, this mechanism doesn’t function properly. There are mainly 2 kinds of diabetes:
During pregnancy, some women may experience high levels of blood sugar. This is known as gestational diabetes.[1][Diabetes](https://www.nhs.uk/conditions/diabetes/ “Diabetes”).NHS,UK.
It is estimated that around 422 million people worldwide suffer from diabetes.[2][Diabetes](https://www.who.int/health-topics/diabetes#tab=tab_1 “Diabetes”). World Health Organization. But this figure doesn’t give us a clear picture of the magnitude of the problem. Many people also suffer from prediabetes, a condition with abnormally high blood sugar levels though it’s not high enough to be characterized as diabetes. These people have a higher risk of developing diabetes.
While modern medicine recommends a healthy diet, regular exercise, and even medication in some cases to deal with diabetes, the ancient science of ayurveda also offers an approach for addressing this condition. Ayurveda implicates hereditary (sahaja) and lifestyle (apathyanimittaja) factors such as an improper diet in the development of diabetes or madhumeha. Madhumeha, which literally translates to having sweet urine like honey, is considered one of twenty urinary disorders (prameha). The ayurvedic ways to control diabetes also emphasise a healthy diet and physical activity. But there will be differences in the approach based on your body constitution (deha prakriti):
Medicinal plants and vegetables have long been an invaluable part of the ayurvedic approach to treating diseases. And bitter gourd for diabetes or bitter melon is considered one of the ways to control diabetes.
Bitter gourd or bitter melon (aka karela) has traditionally been used for a range of medical conditions such as chronic fever, joint pain, jaundice, haemorrhoids, skin diseases, and diseases of the liver and digestive system etc. Also known as karela, it has a bitter (tikta), pungent (katu) taste (rasa) as well as the qualities (guna) of being light (laghu) and dry (ruksha). Ayurveda considers it to be useful in reducing obesity as well as lowering blood sugar. It is thought to promote strength and work as an anti-toxicant.[4][Bitter Gourd (Karela): Benefits, Remedies, Research, Side Effects](https://www.easyayurveda.com/2016/09/20/bitter-gourd-karela-benefits-remedies-research-side-effects/ “Bitter Gourd (Karela): … Continue reading [5]Bortolotti, Massimo, Daniele Mercatelli, and Letizia Polito. “Momordica charantia, a nutraceutical approach for inflammatory related diseases.” Frontiers in pharmacology 10 (2019): 486. [6]Janagal, Bhageshwary, Chandan Singh, Rajendra Prasad Purvia, and Manoj Adlakha. “A review of hypoglycemic effect of Momordica charantia wsr to madhumeh.” International Journal of Ayurveda … Continue reading
It is also a highly nutritious vegetable which can offer you a dose of vitamin C, vitamin A, potassium, zinc, calcium, phosphorus, iron, copper, magnesium, and B-vitamins. It also contains beneficial antioxidants such as zeaxanthin and lutein.[7]Malia Frey.[Bitter Melon Nutrition Facts and Health Benefits](https://www.verywellfit.com/bitter-melon-nutrition-facts-4178970 “Bitter Melon Nutrition Facts and Health Benefits”).Verywell Fit.
An animal study looked at the effect of bitter gourd for diabetes on postprandial glycemic response: blood sugar levels after a meal. It was found that bitter gourd extracts significantly suppressed blood sugar levels after 30 minutes. It is thought to work by inhibiting the activity of an enzyme called alpha-glucosidase. This enzyme helps break down food (carbohydrates) into glucose which is then absorbed into the bloodstream. So by inhibiting it you reduce the sugar released into the bloodstream.[8]Uebanso, Takashi, Hidekazu Arai, Yutaka Taketani, Makiko Fukaya, Hironori Yamamoto, Akira Mizuno, Keisuke Uryu, Takahiko Hada, and Eiji Takeda. “Extracts of Momordica charantia suppress … Continue reading
During the course of a study where rats were fed a high-fat diet for 6 weeks, it was found that those who were also given a bitter gourd extract showed significantly better glucose tolerance and insulin sensitivity. That is, they were able to clear glucose from their bloodstream faster, and their bodies responded better to insulin. This means that bitter gourd for diabetes could possibly help prevent insulin resistance.[9]Yang, Soo Jin, Jung Mook Choi, Se Eun Park, Eun Jung Rhee, Won Young Lee, Ki Won Oh, Sung Woo Park, and Cheol-Young Park. “Preventive effects of bitter gourd (Momordica charantia) against … Continue reading
Glucose tolerance is described as your body’s ability to clear glucose from the bloodstream. People with impaired glucose tolerance have higher than normal blood sugar levels. According to a study, bitter gourd juice significantly improved glucose tolerance in 73% of diabetic patients who participated.[10]Welihinda, J., E. H. Karunanayake, M. H. H. Sheriff, and K. S. A. Jayasinghe. “Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes.” Journal of … Continue reading
Meanwhile, another study found that while a small improvement in glucose tolerance was noticed by adding fried karela for diabetes to the diet, the effect was most noteworthy when raw karela juice was consumed.[11]Leatherdale, B. A., R. K. Panesar, G. Singh, T. W. Atkins, C. J. Bailey, and A. H. Bignell. “Improvement in glucose tolerance due to Momordica charantia (karela).” Br Med J (Clin Res Ed) … Continue reading
Bitter gourd exerts its anti-diabetic effects through various mechanisms, and several useful compounds such as p-insulin and charantin are thought to contribute to these effects.[16] Raman, A., and C. Lau. “Anti-diabetic properties and phytochemistry of Momordica charantia L.(Cucurbitaceae).” Phytomedicine 2, no. 4 (1996): 349-362.
Fruit juice extracts of bitter gourd have been found to act like insulin. Just like insulin, they move sugar into your cells, where they’re used for energy.[17]Cummings, E., H. S. Hundal, H. Wackerhage, M. Hope, M. Belle, E. Adeghate, and J. Singh. “Momordica charantia fruit juice stimulates glucose and amino acid uptakes in L6 myotubes.” … Continue reading
One study found that bitter gourd extracts stimulate insulin release by pancreatic cells from obese and diabetic mice.[18]Welihinda, J., G. Arvidson, E. Gylfe, B. Hellman, and E. Karlsson. “The insulin-releasing activity of the tropical plant momordica charantia.” Acta biologica et medica Germanica 41, no. … Continue reading
Research indicates that bitter gourd can inhibit the enzymes involved in converting food into glucose. This means that less glucose is formed in the body, therefore, less glucose is released into the bloodstream.[19]Shibib, Baizid A., Liakot Ali Khan, and Rafiqur Rahman. “Hypoglycaemic activity of Coccinia indica and Momordica charantia in diabetic rats: depression of the hepatic gluconeogenic enzymes … Continue reading [20]Uebanso, Takashi, Hidekazu Arai, Yutaka Taketani, Makiko Fukaya, Hironori Yamamoto, Akira Mizuno, Keisuke Uryu, Takahiko Hada, and Eiji Takeda. “Extracts of Momordica charantia suppress … Continue reading
References
↑1 | [Diabetes](https://www.nhs.uk/conditions/diabetes/ “Diabetes”).NHS,UK. |
---|---|
↑2 | [Diabetes](https://www.who.int/health-topics/diabetes#tab=tab_1 “Diabetes”). World Health Organization. |
↑3 | [Diabetes: Ayurvedic Treatment, Remedies, Prevention Tips](https://www.easyayurveda.com/2013/11/25/madhumeha-ayurvedic-understanding-diabetes-mellitus/ “Diabetes: Ayurvedic Treatment, Remedies, Prevention Tips”). Easy Ayurveda. |
↑4 | [Bitter Gourd (Karela): Benefits, Remedies, Research, Side Effects](https://www.easyayurveda.com/2016/09/20/bitter-gourd-karela-benefits-remedies-research-side-effects/ “Bitter Gourd (Karela): Benefits, Remedies, Research, Side Effects”). Easy Ayurveda. |
↑5 | Bortolotti, Massimo, Daniele Mercatelli, and Letizia Polito. “Momordica charantia, a nutraceutical approach for inflammatory related diseases.” Frontiers in pharmacology 10 (2019): 486. |
↑6, ↑21 | Janagal, Bhageshwary, Chandan Singh, Rajendra Prasad Purvia, and Manoj Adlakha. “A review of hypoglycemic effect of Momordica charantia wsr to madhumeh.” International Journal of Ayurveda and Pharma Research (2018). |
↑7 | Malia Frey.[Bitter Melon Nutrition Facts and Health Benefits](https://www.verywellfit.com/bitter-melon-nutrition-facts-4178970 “Bitter Melon Nutrition Facts and Health Benefits”).Verywell Fit. |
↑8, ↑20 | Uebanso, Takashi, Hidekazu Arai, Yutaka Taketani, Makiko Fukaya, Hironori Yamamoto, Akira Mizuno, Keisuke Uryu, Takahiko Hada, and Eiji Takeda. “Extracts of Momordica charantia suppress postprandial hyperglycemia in rats.” Journal of nutritional science and vitaminology 53, no. 6 (2007): 482-488. |
↑9 | Yang, Soo Jin, Jung Mook Choi, Se Eun Park, Eun Jung Rhee, Won Young Lee, Ki Won Oh, Sung Woo Park, and Cheol-Young Park. “Preventive effects of bitter gourd (Momordica charantia) against insulin resistance and diabetes are associated with the inhibition of NF-κB and JNK pathways in high-fat-fed OLETF rats.” The Journal of Nutritional Biochemistry 26, no. 3 (2015): 234-240. |
↑10 | Welihinda, J., E. H. Karunanayake, M. H. H. Sheriff, and K. S. A. Jayasinghe. “Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes.” Journal of ethnopharmacology 17, no. 3 (1986): 277-282. |
↑11 | Leatherdale, B. A., R. K. Panesar, G. Singh, T. W. Atkins, C. J. Bailey, and A. H. Bignell. “Improvement in glucose tolerance due to Momordica charantia (karela).” Br Med J (Clin Res Ed) 282, no. 6279 (1981): 1823-1824. |
↑12 | [Diabetic Retinopathy](https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/diabetic-retinopathy “Diabetic Retinopathy”). National Institutes of Health. |
↑13 | Srivastava, Y., H. Venkatakrishna-Bhatt, and Y. Verma. “Effect of Monordica charantia Linn. pomous aqueous extract on cataractogenesis in murrin alloxan diabetics.” Pharmacological research communications 20, no. 3 (1988): 201-209. |
↑14 | [Peripheral neuropathy](https://www.nhs.uk/conditions/peripheral-neuropathy/ “Peripheral neuropathy”) NHS,UK. |
↑15 | Singh, J., E. Cumming, G. Manoharan, H. Kalasz, and E. Adeghate. “Medicinal Chemistry of the Anti-Diabetic Effects of Momordica charantia: Active Constituents and Modes of Actions. The Open Medicinal Chemistry Journal, 5, 70-77.” (2011). |
↑16, ↑22 | Raman, A., and C. Lau. “Anti-diabetic properties and phytochemistry of Momordica charantia L.(Cucurbitaceae).” Phytomedicine 2, no. 4 (1996): 349-362. |
↑17 | Cummings, E., H. S. Hundal, H. Wackerhage, M. Hope, M. Belle, E. Adeghate, and J. Singh. “Momordica charantia fruit juice stimulates glucose and amino acid uptakes in L6 myotubes.” Molecular and cellular biochemistry 261, no. 1 (2004): 99-104. |
↑18 | Welihinda, J., G. Arvidson, E. Gylfe, B. Hellman, and E. Karlsson. “The insulin-releasing activity of the tropical plant momordica charantia.” Acta biologica et medica Germanica 41, no. 12 (1982): 1229-1240. |
↑19 | Shibib, Baizid A., Liakot Ali Khan, and Rafiqur Rahman. “Hypoglycaemic activity of Coccinia indica and Momordica charantia in diabetic rats: depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1, 6-bisphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase.” Biochemical Journal 292, no. 1 (1993): 267-270. |
↑23 | [Bitter Gourd Nutrition Facts and Health Benefits](https://www.verywellfit.com/bitter-gourd-nutrition-facts-4178970 “Bitter Gourd Nutrition Facts and Health Benefits”).Verywell Health. |
Dr. Anand R Dwivedi is an Ayurevedacharya from Mumbai University, 1987. He has been practicing Ayurveda since 1988. He has a special interest in the treatment of chronic illnesses with the help of Ayurveda. He has been associated with Kapiva since 2015 and helping people lead a well-balanced lifestyle through his deep knowledge of Ayurveda.
Made by Ms. Sindhu Vas, M.Sc. Food Science & Nutrition Medically Reviewed by: Dr. Prajna, BAMS, MD Ayurveda…
Read MoreMade by Ms. Sindhu Vas, M.Sc. Food Science & Nutrition Medically Reviewed by: Dr. Prajna, BAMS, MD Ayurveda…
Read MoreMade by Ms. Sindhu Vas, M.Sc. Food Science & Nutrition Medically Reviewed by: Dr. Prajna,…
Read MoreMade by Ms. Sindhu Vas, M.Sc. Food Science & Nutrition Medically Reviewed by: Dr. Prajna, BAMS, MD Ayurveda…
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